Vhf08270 details

Gene vhfRNAi AccessionVhf08270
Gene SymbolBCS1
Gene DescriptionMitochondrial chaperone BCS1 (h-BCS1) (BCS1-like protein)
Gene Name in PaperBCS1
GroupHost Factor
Ensembl Gene IDENST00000359273 ENST00000392109 ENST00000392110 ENST00000392111 ENST00000412366 ENST00000431802 ENST00000439945 
UniProt IDQ9Y276
Entrez Gene ID617
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)