Vhf08249 details

Gene vhfRNAi AccessionVhf08249
Gene SymbolZFAN6
Gene DescriptionAN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3)
Gene Name in PaperZFAN6
GroupHost Factor
Ensembl Gene IDENST00000261749 ENST00000558087 ENST00000558494 ENST00000559157 ENST00000559775 ENST00000559835 ENST00000561060 ENST00000613266 ENST00000616533 ENST00000618205 
UniProt IDQ6FIF0
Entrez Gene ID54469
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)