Vhf08248 details

Gene vhfRNAi AccessionVhf08248
Gene SymbolZPI
Gene DescriptionProtein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)
Gene Name in PaperZPI
GroupHost Factor
Ensembl Gene IDENST00000261994 ENST00000393096 ENST00000554173 ENST00000614630 
UniProt IDQ9UK55
Entrez Gene ID51156
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)