RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08214 |
Gene Symbol | SC6A2 | |
Gene Description | Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) | |
Gene Name in Paper | SC6A2 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000219833 ENST00000379906 ENST00000567238 ENST00000568943 | |
UniProt ID | P23975 | |
Entrez Gene ID | 6530 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |