Vhf08194 details

Gene vhfRNAi AccessionVhf08194
Gene SymbolRT12
Gene Description28S ribosomal protein S12, mitochondrial (MRP-S12) (S12mt) (MT-RPS12)
Gene Name in PaperRT12
GroupHost Factor
Ensembl Gene IDENST00000308018 ENST00000402029 ENST00000407800 ENST00000634246 ENST00000634400 ENST00000634704 
UniProt IDO15235
Entrez Gene ID6183
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)