RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08187 |
Gene Symbol | TAD2A | |
Gene Description | Transcriptional adapter 2-alpha (Transcriptional adapter 2-like) (ADA2-like protein) | |
Gene Name in Paper | TAD2A | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000617828 ENST00000622522 ENST00000633468 ENST00000633584 | |
UniProt ID | O75478 | |
Entrez Gene ID | 6871 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |