Vhf08176 details

Gene vhfRNAi AccessionVhf08176
Gene SymbolDRA
Gene DescriptionHLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
Gene Name in PaperDRA
GroupHost Factor
Ensembl Gene IDENST00000383127 ENST00000383259 ENST00000395388 ENST00000411524 ENST00000414698 ENST00000416883 ENST00000442960 
UniProt IDP01903
Entrez Gene ID3122
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)