Vhf08161 details

Gene vhfRNAi AccessionVhf08161
Gene SymbolGLIS2
Gene DescriptionZinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein)
Gene Name in PaperGLIS2
GroupHost Factor
Ensembl Gene IDENST00000262366 ENST00000433375 ENST00000612491 ENST00000633051 
UniProt IDQ9BZE0
Entrez Gene ID84662
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)