Vhf08145 details

Gene vhfRNAi AccessionVhf08145
Gene SymbolF1142
Gene DescriptionProtein FAM114A2
Gene Name in PaperF1142
GroupHost Factor
Ensembl Gene IDENST00000351797 ENST00000520667 ENST00000522858 
UniProt IDQ9NRY5
Entrez Gene ID10827
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)