Vhf08138 details

Gene vhfRNAi AccessionVhf08138
Gene SymbolKLC4
Gene DescriptionKinesin light chain 4 (KLC 4) (Kinesin-like protein 8)
Gene Name in PaperKLC4
GroupHost Factor
Ensembl Gene IDENST00000259708 ENST00000347162 ENST00000394056 ENST00000453940 ENST00000458460 ENST00000467906 ENST00000479388 
UniProt IDQ9NSK0
Entrez Gene ID89953
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)