RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf08135 |
Gene Symbol | NEUR4 | |
Gene Description | Sialidase-4 (EC 3.2.1.18) (N-acetyl-alpha-neuraminidase 4) | |
Gene Name in Paper | NEUR4 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000325935 ENST00000391969 ENST00000404257 ENST00000405370 ENST00000407683 ENST00000616490 ENST00000618866 ENST00000621851 ENST00000626600 ENST00000630923 | |
UniProt ID | Q8WWR8 | |
Entrez Gene ID | 129807 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |