Vhf08113 details

Gene vhfRNAi AccessionVhf08113
Gene SymbolMOAP1
Gene DescriptionModulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4)
Gene Name in PaperMOAP1
GroupHost Factor
Ensembl Gene IDENST00000298894 ENST00000556883 ENST00000616515 ENST00000627896 
UniProt IDQ96BY2
Entrez Gene ID64112
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)