Vhf08085 details

Gene vhfRNAi AccessionVhf08085
Gene SymbolDQA2
Gene DescriptionHLA class II histocompatibility antigen, DQ alpha 2 chain (DX alpha chain) (HLA class II histocompatibility antigen, DQ(6) alpha chain) (HLA-DQA1) (MHC class II DQA2)
Gene Name in PaperDQA2
GroupHost Factor
Ensembl Gene IDENST00000241802 ENST00000374940 ENST00000415898 ENST00000443184 ENST00000446482 ENST00000447735 ENST00000449560 ENST00000453672 ENST00000546801 ENST00000551533 
UniProt IDP01906
Entrez Gene ID3118
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)