Vhf08077 details

Gene vhfRNAi AccessionVhf08077
Gene SymbolTPPP3
Gene DescriptionTubulin polymerization-promoting protein family member 3 (TPPP/p20)
Gene Name in PaperTPPP3
GroupHost Factor
Ensembl Gene IDENST00000290942 ENST00000393957 ENST00000562206 ENST00000564104 
UniProt IDQ9BW30
Entrez Gene ID51673
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)