Vhf08065 details

Gene vhfRNAi AccessionVhf08065
Gene SymbolFANCA
Gene DescriptionFanconi anemia group A protein (Protein FACA)
Gene Name in PaperFANCA
GroupHost Factor
Ensembl Gene IDENST00000389301 ENST00000389302 ENST00000568369 
UniProt IDO15360
Entrez Gene ID2175
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)