Vhf08059 details

Gene vhfRNAi AccessionVhf08059
Gene SymbolFA21C
Gene DescriptionWASH complex subunit FAM21C (Vaccinia virus penetration factor) (VPEF)
Gene Name in PaperFA21C
GroupHost Factor
Ensembl Gene IDENST00000374362 ENST00000537517 ENST00000540872 
UniProt IDQ9Y4E1
Entrez Gene ID253725
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)