Vhf08042 details

Gene vhfRNAi AccessionVhf08042
Gene SymbolTGIF1
Gene DescriptionHomeobox protein TGIF1 (5'-TG-3'-interacting factor 1)
Gene Name in PaperTGIF1
GroupHost Factor
Ensembl Gene IDENST00000330513 ENST00000343820 ENST00000345133 ENST00000400167 ENST00000401449 ENST00000405385 ENST00000407501 ENST00000472042 ENST00000548489 ENST00000551541 ENST00000618001 
UniProt IDQ15583
Entrez Gene ID7050
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)