Vhf08033 details

Gene vhfRNAi AccessionVhf08033
Gene SymbolMBD1
Gene DescriptionMethyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1)
Gene Name in PaperMBD1
GroupHost Factor
Ensembl Gene IDENST00000269468 ENST00000269471 ENST00000339998 ENST00000347968 ENST00000353909 ENST00000382948 ENST00000398488 ENST00000398493 ENST00000457839 ENST00000585595 ENST00000585672 ENST00000587605 ENST00000588937 ENST00000590208 ENST00000591416 ENST00000591535 
UniProt IDQ9UIS9
Entrez Gene ID4152
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)