RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf08033 |
| Gene Symbol | MBD1 | |
| Gene Description | Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1) | |
| Gene Name in Paper | MBD1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000269468 ENST00000269471 ENST00000339998 ENST00000347968 ENST00000353909 ENST00000382948 ENST00000398488 ENST00000398493 ENST00000457839 ENST00000585595 ENST00000585672 ENST00000587605 ENST00000588937 ENST00000590208 ENST00000591416 ENST00000591535 | |
| UniProt ID | Q9UIS9 | |
| Entrez Gene ID | 4152 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |