RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07985 |
| Gene Symbol | H2B1C | |
| Gene Description | Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l) | |
| Gene Name in Paper | H2B1C | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000314332 ENST00000356530 ENST00000377733 ENST00000396984 ENST00000541790 ENST00000614097 ENST00000634910 | |
| UniProt ID | P62807 | |
| Entrez Gene ID | 3017;8339;8343;8344;8346;8347 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |