Vhf07944 details

Gene vhfRNAi AccessionVhf07944
Gene SymbolVAT1
Gene DescriptionSynaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-)
Gene Name in PaperVAT1
GroupHost Factor
Ensembl Gene IDENST00000355653 ENST00000420567 ENST00000587173 
UniProt IDQ99536
Entrez Gene ID10493
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)