Vhf07943 details

Gene vhfRNAi AccessionVhf07943
Gene SymbolVMAT1
Gene DescriptionChromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)
Gene Name in PaperVMAT1
GroupHost Factor
Ensembl Gene IDENST00000265808 ENST00000276373 ENST00000381608 ENST00000437980 ENST00000440926 ENST00000519026 
UniProt IDP54219
Entrez Gene ID6570
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)