RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07841 |
| Gene Symbol | OSCAR | |
| Gene Description | Osteoclast-associated immunoglobulin-like receptor (Osteoclast-associated receptor) (hOSCAR) (Polymeric immunoglobulin receptor 3) (PIgR-3) (PIgR3) (Poly-Ig receptor 3) | |
| Gene Name in Paper | OSCAR | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000284648 ENST00000391761 ENST00000610577 ENST00000610915 ENST00000610985 ENST00000611143 ENST00000611480 ENST00000611535 ENST00000611715 ENST00000611719 ENST00000611918 ENST00000611987 ENST00000612289 ENST00000612406 ENST00000612953 ENST00000613426 ENST00000613814 ENST00000614003 ENST00000614380 ENST00000615074 ENST00000615546 ENST00000616215 ENST00000616227 ENST00000616232 ENST00000616461 ENST00000616758 ENST00000617187 ENST00000617210 ENST00000617622 ENST00000617834 ENST00000617993 ENST00000618710 ENST00000619170 ENST00000619287 ENST00000619631 ENST00000620283 ENST00000620647 ENST00000621284 ENST00000621290 ENST00000621328 ENST00000621506 ENST00000621788 ENST00000622288 ENST00000622326 | |
| UniProt ID | Q8IYS5 | |
| Entrez Gene ID | 126014 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |