Vhf07784 details

Gene vhfRNAi AccessionVhf07784
Gene SymbolMBP
Gene DescriptionMyelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
Gene Name in PaperMBP
GroupHost Factor
Ensembl Gene IDENST00000355994 ENST00000359645 ENST00000382582 ENST00000397860 ENST00000397863 ENST00000397865 ENST00000397866 ENST00000580402 
UniProt IDP02686
Entrez Gene ID4155
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)