Vhf07780 details

Gene vhfRNAi AccessionVhf07780
Gene SymbolCEP41
Gene DescriptionCentrosomal protein of 41 kDa (Cep41) (Testis-specific gene A14 protein)
Gene Name in PaperCEP41
GroupHost Factor
Ensembl Gene IDENST00000223208 ENST00000343969 ENST00000489512 ENST00000541543 ENST00000616628 
UniProt IDQ9BYV8
Entrez Gene ID95681
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)