RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07767 |
| Gene Symbol | GIT2 | |
| Gene Description | ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) | |
| Gene Name in Paper | GIT2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000355312 ENST00000361006 ENST00000457474 ENST00000547815 ENST00000553118 | |
| UniProt ID | Q14161 | |
| Entrez Gene ID | 9815 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |