Vhf07730 details

Gene vhfRNAi AccessionVhf07730
Gene SymbolHXB9
Gene DescriptionHomeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E)
Gene Name in PaperHXB9
GroupHost Factor
Ensembl Gene IDENST00000311177 
UniProt IDP17482
Entrez Gene ID3219
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)