RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07711 |
Gene Symbol | 5NT1B | |
Gene Description | Cytosolic 5'-nucleotidase 1B (cN1B) (EC 3.1.3.5) (Autoimmune infertility-related protein) (Cytosolic 5'-nucleotidase IB) (cN-IB) | |
Gene Name in Paper | 5NT1B | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000304081 ENST00000359846 | |
UniProt ID | Q96P26 | |
Entrez Gene ID | 100526794;93034 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |