Vhf07689 details

Gene vhfRNAi AccessionVhf07689
Gene SymbolF177A
Gene DescriptionProtein FAM177A1
Gene Name in PaperF177A
GroupHost Factor
Ensembl Gene IDENST00000280987 ENST00000382406 ENST00000396472 
UniProt IDQ8N128
Entrez Gene ID283635
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)