Vhf07670 details

Gene vhfRNAi AccessionVhf07670
Gene SymbolDPA1
Gene DescriptionHLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1)
Gene Name in PaperDPA1
GroupHost Factor
Ensembl Gene IDENST00000374808 ENST00000383224 ENST00000415247 ENST00000419277 ENST00000422504 ENST00000443117 ENST00000454805 ENST00000515317 ENST00000617497 
UniProt IDP20036
Entrez Gene ID3113
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)