Vhf07669 details

Gene vhfRNAi AccessionVhf07669
Gene SymbolZN347
Gene DescriptionZinc finger protein 347 (Zinc finger protein 1111)
Gene Name in PaperZN347
GroupHost Factor
Ensembl Gene IDENST00000334197 ENST00000452676 ENST00000601469 
UniProt IDQ96SE7
Entrez Gene ID84671
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)