Vhf07666 details

Gene vhfRNAi AccessionVhf07666
Gene SymbolASXL1
Gene DescriptionPutative Polycomb group protein ASXL1 (Additional sex combs-like protein 1)
Gene Name in PaperASXL1
GroupHost Factor
Ensembl Gene IDENST00000375687 ENST00000613218 ENST00000620121 
UniProt IDQ8IXJ9
Entrez Gene ID171023
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)