Vhf07662 details

Gene vhfRNAi AccessionVhf07662
Gene SymbolDLGP1
Gene DescriptionDisks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene Name in PaperDLGP1
GroupHost Factor
Ensembl Gene IDENST00000315677 ENST00000400145 ENST00000400147 ENST00000400155 ENST00000534970 ENST00000539435 ENST00000581527 ENST00000581699 ENST00000584874 
UniProt IDO14490
Entrez Gene ID9229
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)