Vhf07653 details

Gene vhfRNAi AccessionVhf07653
Gene SymbolLMBL3
Gene DescriptionLethal(3)malignant brain tumor-like protein 3 (H-l(3)mbt-like protein 3) (L(3)mbt-like protein 3) (MBT-1)
Gene Name in PaperLMBL3
GroupHost Factor
Ensembl Gene IDENST00000361794 ENST00000368136 ENST00000368139 ENST00000526019 ENST00000529410 ENST00000533560 
UniProt IDQ96JM7
Entrez Gene ID84456
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)