Vhf07616 details

Gene vhfRNAi AccessionVhf07616
Gene SymbolAT1B4
Gene DescriptionProtein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m)
Gene Name in PaperAT1B4
GroupHost Factor
Ensembl Gene IDENST00000218008 ENST00000361319 
UniProt IDQ9UN42
Entrez Gene ID23439
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)