RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07614 |
| Gene Symbol | CAC1C | |
| Gene Description | Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2) | |
| Gene Name in Paper | CAC1C | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000344100 ENST00000347598 ENST00000399591 ENST00000399595 ENST00000399597 ENST00000399601 ENST00000399603 ENST00000399606 ENST00000399621 ENST00000399629 ENST00000399637 ENST00000399638 ENST00000399641 ENST00000399644 ENST00000399649 ENST00000399655 ENST00000402845 | |
| UniProt ID | Q13936 | |
| Entrez Gene ID | 775 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |