RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07607 |
| Gene Symbol | SDF1 | |
| Gene Description | Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)] | |
| Gene Name in Paper | SDF1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000343575 ENST00000374426 ENST00000374429 ENST00000395793 ENST00000395794 ENST00000395795 | |
| UniProt ID | P48061 | |
| Entrez Gene ID | 6387 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |