Vhf07597 details

Gene vhfRNAi AccessionVhf07597
Gene SymbolDIP2A
Gene DescriptionDisco-interacting protein 2 homolog A (DIP2 homolog A)
Gene Name in PaperDIP2A
GroupHost Factor
Ensembl Gene IDENST00000400274 ENST00000417564 ENST00000435722 ENST00000457905 ENST00000466639 
UniProt IDQ14689
Entrez Gene ID23181
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)