RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07590 |
Gene Symbol | SIG10 | |
Gene Description | Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2) | |
Gene Name in Paper | SIG10 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000339313 ENST00000353836 ENST00000436984 ENST00000439889 ENST00000441969 ENST00000442846 | |
UniProt ID | Q96LC7 | |
Entrez Gene ID | 89790 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |