Vhf07587 details

Gene vhfRNAi AccessionVhf07587
Gene SymbolDUS8
Gene DescriptionDual specificity protein phosphatase 8 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH-5)
Gene Name in PaperDUS8
GroupHost Factor
Ensembl Gene IDENST00000331588 ENST00000397374 ENST00000610856 ENST00000617829 ENST00000625578 ENST00000629053 
UniProt IDQ13202
Entrez Gene ID1850
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)