Vhf07579 details

Gene vhfRNAi AccessionVhf07579
Gene SymbolCJ099
Gene DescriptionSecreted protein C10orf99 (Antimicrobial peptide-57) (AP-57) (Colon-derived SUSD2 binding factor) (CSBF)
Gene Name in PaperCJ099
GroupHost Factor
Ensembl Gene IDENST00000372126 
UniProt IDQ6UWK7
Entrez Gene ID387695
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)