Vhf07577 details

Gene vhfRNAi AccessionVhf07577
Gene SymbolO51B2
Gene DescriptionOlfactory receptor 51B2 (Odorant receptor HOR5'beta3) (Olfactory receptor 51B1)
Gene Name in PaperO51B2
GroupHost Factor
Ensembl Gene IDENST00000328813 ENST00000624064 ENST00000624187 
UniProt IDQ9Y5P1
Entrez Gene ID79345
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)