Vhf07564 details

Gene vhfRNAi AccessionVhf07564
Gene SymbolTLR10
Gene DescriptionToll-like receptor 10 (CD antigen CD290)
Gene Name in PaperTLR10
GroupHost Factor
Ensembl Gene IDENST00000308973 ENST00000361424 ENST00000506111 ENST00000508334 ENST00000613579 ENST00000622002 
UniProt IDQ9BXR5
Entrez Gene ID81793
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)