Vhf07556 details

Gene vhfRNAi AccessionVhf07556
Gene SymbolGPVI
Gene DescriptionPlatelet glycoprotein VI (GPVI) (Glycoprotein 6)
Gene Name in PaperGPVI
GroupHost Factor
Ensembl Gene IDENST00000310373 ENST00000333884 ENST00000417454 ENST00000610596 ENST00000610746 ENST00000611436 ENST00000612096 ENST00000612184 ENST00000612862 ENST00000613649 ENST00000613801 ENST00000614662 ENST00000614889 ENST00000615407 ENST00000616319 ENST00000616456 ENST00000617954 ENST00000619136 ENST00000621278 ENST00000622279 ENST00000622589 ENST00000622653 
UniProt IDQ9HCN6
Entrez Gene ID51206
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)