RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07551 |
| Gene Symbol | PEX5 | |
| Gene Description | Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) | |
| Gene Name in Paper | PEX5 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000266563 ENST00000266564 ENST00000420616 ENST00000434354 ENST00000455147 | |
| UniProt ID | P50542 | |
| Entrez Gene ID | 5830 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |