Vhf07543 details

Gene vhfRNAi AccessionVhf07543
Gene SymbolSUOX
Gene DescriptionSulfite oxidase, mitochondrial (EC 1.8.3.1)
Gene Name in PaperSUOX
GroupHost Factor
Ensembl Gene IDENST00000266971 ENST00000356124 ENST00000394109 ENST00000394115 ENST00000548274 ENST00000550065 
UniProt IDP51687
Entrez Gene ID6821
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)