Vhf07530 details

Gene vhfRNAi AccessionVhf07530
Gene SymbolB2MG
Gene DescriptionBeta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene Name in PaperB2MG
GroupHost Factor
Ensembl Gene IDENST00000558401 ENST00000559916 ENST00000561424 ENST00000617605 ENST00000631573 ENST00000631728 
UniProt IDP61769
Entrez Gene ID567
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)