RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf07530 |
Gene Symbol | B2MG | |
Gene Description | Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3] | |
Gene Name in Paper | B2MG | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000558401 ENST00000559916 ENST00000561424 ENST00000617605 ENST00000631573 ENST00000631728 | |
UniProt ID | P61769 | |
Entrez Gene ID | 567 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |