RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf07521 |
| Gene Symbol | MARK2 | |
| Gene Description | Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b) | |
| Gene Name in Paper | MARK2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000350490 ENST00000361128 ENST00000402010 ENST00000408948 ENST00000508192 ENST00000509502 ENST00000513765 | |
| UniProt ID | Q7KZI7 | |
| Entrez Gene ID | 2011 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |