Vhf07518 details

Gene vhfRNAi AccessionVhf07518
Gene SymbolRFX5
Gene DescriptionDNA-binding protein RFX5 (Regulatory factor X 5)
Gene Name in PaperRFX5
GroupHost Factor
Ensembl Gene IDENST00000290524 ENST00000368870 ENST00000452671 
UniProt IDP48382
Entrez Gene ID5993
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)