Vhf07517 details

Gene vhfRNAi AccessionVhf07517
Gene SymbolHDAC9
Gene DescriptionHistone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene Name in PaperHDAC9
GroupHost Factor
Ensembl Gene IDENST00000401921 ENST00000405010 ENST00000406451 ENST00000417496 ENST00000428307 ENST00000432645 ENST00000441542 ENST00000456174 ENST00000524023 
UniProt IDQ9UKV0
Entrez Gene ID9734
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)