Vhf07513 details

Gene vhfRNAi AccessionVhf07513
Gene SymbolPAX8
Gene DescriptionPaired box protein Pax-8
Gene Name in PaperPAX8
GroupHost Factor
Ensembl Gene IDENST00000263334 ENST00000263335 ENST00000348715 ENST00000397647 ENST00000429538 
UniProt IDQ06710
Entrez Gene ID7849
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)